EasySep-5010 HPLC System – Modular High-Performance Liquid Chromatography Platform

EasySep-5010 HPLC System — Modular Platform for Pharmaceutical Analysis

The EasySep-5010 HPLC System is a modular, fully automated quaternary UHPLC platform. Its four-channel pump can simultaneously deliver up to four mobile phases, paired with an upgraded injection system, separation system, and detection system, and a chromatography workstation with a built-in database — delivering reliable test data and improving laboratory analysis efficiency.

The system's four pump channels can be freely combined to meet different flow and method requirements. The chromatography workstation controls all modules together and supports fully automated, long-duration unattended sequence runs — improving analytical throughput while keeping operation simple and maintenance cost low.

System Modules

1. Quaternary Solvent Delivery Pump

• Four-channel quaternary pump design delivers up to four mobile phases simultaneously for flexible gradient method development
• Built-in four-channel online degasser automatically removes dissolved gas from mobile phases, preventing bubble formation
• Built-in automated flush/cleaning function with configurable wash programs for unattended in-line seal cleaning

2. Column Thermostat

• Software-controlled temperature regulation with real-time temperature display
• Holds multiple chromatography columns simultaneously, with software-configurable automatic column switching
• Wide control range with fast ramp-up to reduce equilibration time between runs

3. UV/Vis Detector

• Dual optical path design enables simultaneous dual-wavelength detection, plus time-programmed wavelength and static wavelength-scan modes
• Automatically logs fault codes, lamp usage hours, and component-replacement history, with power-on self-test

4. DAD — Diode Array Detector

• Diode-array detection technology enables simultaneous multi-wavelength monitoring, full 3D spectral acquisition, and peak-purity calculation
• Digital and analog signal outputs for compatibility with third-party chromatography data software

5. Autosampler

• Fully software-controlled autosampler enables unattended sample analysis, reducing operator time
• Flexible injection modes with selectable sample-loop volumes to match different injection-volume requirements
• Multiple wash/rinse modes minimize cross-contamination between injections

6. Chromatography Data System

• Strict user permission management and audit trail, with a built-in database supporting compliance with relevant regulatory requirements
• Extensible instrument control — supports simultaneous control of up to four systems through one graphical interface
• Centralized workstation controls all modules (pump, detectors, column oven, autosampler), monitors operating parameters and status, and manages data acquisition, chromatogram analysis, and report printing
• Supports sequence/batch processing and event-triggered automation for long, unattended analytical runs

System Configuration

Quaternary Pump: 4-channel solvent delivery, built-in online degasser, automated seal-wash cleaning

Column Thermostat: Software-controlled temperature regulation, multi-column capacity with automatic switching

UV/Vis Detector: Dual optical path, simultaneous dual-wavelength detection

Diode Array Detector (DAD): Multi-wavelength simultaneous detection, 3D spectral acquisition, peak-purity calculation

Autosampler: Fully automated injection, multiple injection modes and wash cycles

Chromatography Data System: Multi-user permissions, audit trail, simultaneous control of up to 4 instruments

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Frequently Asked Questions

Q: Is the EasySep-5010 HPLC System modular?

A: Yes. The EasySep-5010 integrates a quaternary solvent delivery pump, column thermostat, UV/Vis detector, diode array detector (DAD), autosampler, and chromatography data system as independent modules. The pump's four channels can be freely combined to meet different flow and method requirements. Contact us to discuss the module configuration for your lab.

Q: What's the difference between the UV/Vis detector and the DAD detector?

A: The UV/Vis detector uses a dual optical path for simultaneous dual-wavelength detection, with time-programmed wavelength and static wavelength-scan modes. The DAD (diode array detector) uses diode-array detection technology for simultaneous multi-wavelength monitoring, full 3D spectral acquisition, and peak-purity calculation. Contact us to discuss which configuration fits your method.

Q: Does the EasySep-5010 support data integrity requirements for GMP labs?

A: Yes. The chromatography data system provides strict user permission management and an audit trail, with a built-in database supporting compliance with relevant regulatory and data-integrity requirements. Contact us to discuss documentation for your regulatory environment.