Complete ODF Film Manufacturing Solution
Complete ODF Film Manufacturing Solution
HUANGHAI delivers a complete, modular solution for Oral Dissolvable Film (ODF) manufacturing — covering everything from precise liquid preparation to high-precision coating, and automated cutting & packaging. Built to meet GMP standards, our systems scale from pilot to commercial production.
1. ODF Liquid Preparation System
Why It Matters
Consistent film quality begins with properly prepared liquids. Inadequate dispersion, poor mixing, or uncontrolled temperature can compromise the entire batch — affecting film uniformity, API distribution, and regulatory compliance.
Application Scenarios
- Pediatric oral films with suspended APIs
- Polymer matrix mixing for transdermal patches
- Ethanol-water solubilization for poorly soluble drugs
- Multi-batch formulation for CRO/CDMO pilot trials
Optional Modules
- Jacketed stainless steel tanks with CIP/SIP capabilities
- Digital PID controllers for temperature and shear rate
- Inline filtration & recirculation loops
- Real-time volume, level, and flow sensors
Technical Overview
- Volume: 30–500L (customizable)
- Control System: PLC + Touchscreen HMI
- Cleaning: Optional CIP/SIP
- Precision: Temp ±0.5°C, Mixing uniformity ±2%
- Material: 316L stainless steel (GMP-compliant)
2. Precision Coating System (ODF & Transdermal Patches)
Why It Matters
Coating thickness and uniformity are critical for dosage accuracy and film functionality. HUANGHAI’s MJ150 and MJ150‑L provide robust control over coating speed, film thickness, and drying curve — suitable for both pharma-grade ODFs and transdermal patches.
Application Scenarios
- Bilayer or dual-API oral films
- Nicotine or lidocaine patch applications
- Zinc, probiotic, or melatonin supplement films
- Flavored pediatric dissolvable film formulations
Optional Modules
- Online thickness measurement scanner
- Dual-component coating heads
- Inert gas drying tunnels
- HEPA-filtered hot air drying zones
- Auto tension control + film shortage alert
Technical Overview
MJ150 – Commercial Coating Line
- Coating Width: 130 mm
- Film Thickness: 0.1–2 mm
- Speed: 0.2–5 m/min
- Drying Tunnel Length: 6 m
- Temperature Range: up to 120°C
- Power: 12 kW
- Machine Size: 9500 × 1400 × 2150 mm
MJ150-L – Pilot Coating Line
- Coating Width: 130 mm
- Film Thickness: 0.1–2 mm
- Speed: 0.2–3 m/min
- Drying Tunnel Length: 2.5 m
- Temperature Range: up to 120°C
- Power: 15 kW
- Machine Size: 2200 × 1400 × 2150 mm
Related Equipment
3. Film Slitting & Packaging Automation
Why It Matters
Final packaging defines product integrity, especially for regulated pharmaceutical or nutraceutical films. HUANGHAI’s MJF180 combines precision slitting, sealing, and rejection inspection to ensure consistent output and full traceability.
Application Scenarios
- Unit-dose pouch packaging
- Multi-strip format for combo therapies
- Export-quality packaging for global markets
- High-throughput production of large SKU sets
Optional Modules
- Defective film auto-rejection
- Batch number printer + barcode
- Vision inspection + audit trail logging
Technical Overview
- Speed: 0.5–3 m/min
- Cutting Length: 13–35 mm
- Precision: ±0.1 mm
- Sealing Temp: up to 180°C
- Power: 10 kW
- Machine Size: 5200 × 1450 × 2000 mm
- Control System: Touchscreen HMI + Audit Logs
- Compliance: GMP + FDA 21 CFR Part 11