Multi-Formula ODF Coating Solution
Precision Multi-Formula Coating for ODFs — Powered by CN117323228A
HUANGHAI’s patented Slitting-Type Film Coating Device (CN117323228A) is a pharmaceutical-grade innovation designed to enable the simultaneous coating of multiple formulations on a single oral dissolvable film (ODF) base — ideal for combination therapies, fixed-dose regimens, and functional health products.
The Challenge in Multi-Formula ODF Production
Producing multi-API or layered oral films is inherently complex. Traditional methods often involve multiple coating runs or secondary shaping, which leads to:
- Increased raw material waste
- Inconsistent API dosage ratios
- Higher energy and labor costs
- Lower manufacturing yield and throughput
HUANGHAI’s Solution: Strip-Based Coating Innovation
Our patented system enables simultaneous slitting and coating of multiple film lanes in one continuous pass — streamlining production and preserving formulation integrity. Key features include:
- Independent formulation channels with dedicated feed grooves
- Adjustable strip width and layout based on target dosage
- One-step transition from coating to cutting, without reshaping
- Real-time control of strip dimensions and output parameters
The result: One film, multiple formulations, zero compromise.
Application Scenarios
This system is ideal for:
- Fixed-dose combination (FDC) prescription drugs
- Layer-sensitive or incompatible APIs
- Custom release profiles within a single film
- Precision nutraceuticals or cannabinoid formulations
Key Benefits
- Save 20–30% in material loss via simultaneous coating
- Preserve exact API ratios per lane/strip
- Reduce equipment runs and downstream processing
- GMP-compliant design, scalable to commercial volumes
Why HUANGHAI
With over 40 years of experience in pharmaceutical manufacturing systems, HUANGHAI is more than a machine supplier — we are a strategic development partner. This patented technology was developed in collaboration with formulation scientists to meet real-world production needs in both China and global markets.
Patent Reference
- Patent No.: CN117323228A
- Title: Slitting-type Film Coating Device and Film Agent Preparation Method
- Applicant: Shanghai Modern Pharmaceutical Engineering Research Center, HUANGHAI
- Publication Date: Jan 2, 2024
- View Full Patent on Google Patents →
Frequently Asked Questions
What is the difference between an ODF film and a transdermal patch?
Oral dissolving films (ODF) dissolve on or under the tongue within seconds to minutes; transdermal patches stick to the skin and release the API over hours to days. Both are made by solvent-cast film coating, and the MJ Pro coating platform can be built for either — the application is set before the machine is manufactured.
What output can I expect from Huanghai ODF machines?
MJ150-RD about 1,200 films per hour for formulation screening; MJ150-Lab 8,000–10,000 films per hour for pilot and clinical batches; MJ150 about 30,000 films per hour (Gen I) for commercial production. For packaging, the MJ180 cuts and packs about 11,900 films per hour (Gen I); the EZ320 (about 9,000 films per hour) is for food-grade films only.
What drying technology is used?
The MJ150 production line uses a hot-air parallel-flow drying tunnel based on Academician Hou Huimin's patent CN201668734U. The MJ150-RD and MJ150-Lab use oven drying.
Can Huanghai machines coat multi-formula (striped) films?
Yes. Huanghai's patent CN117323228A covers stripe coating that applies two formulations side by side in one pass, useful for fixed-dose combination films.