How to choose a moisture analyzer for pharmaceutical powders
A halogen moisture analyzer heats the sample with a halogen lamp and weighs it continuously; the weight lost on drying (LOD) gives the moisture content. The HQ Series electronic moisture analyzer in the Huanghai Pharmaceutical Instruments catalog measures 0–100% moisture with ±0.5% accuracy at 60–160 °C, which suits powders, granules and tablets before and after compression. Choose HQ-501, or HQ-501 CE where CE marking is required.
Model comparison
| Model | Method | Range and accuracy | Heating | Certification |
|---|---|---|---|---|
| HQ-501 | Halogen loss on drying | 0–100%, ±0.5% | 60–160 °C (±2 °C), 0–120 min | Standard version |
| HQ-501 CE | Halogen loss on drying | 0–100%, ±0.5% | 60–160 °C (±2 °C), 0–120 min | CE certified |
How to choose
- Fast routine checks of powders and granules, for example before tableting: a halogen LOD analyzer gives a result in minutes.
- Water specifically, trace water, or samples that lose other volatiles on heating: use Karl Fischer titration (KFT-50VC) instead.
- Instruments used or resold in the EU: choose HQ-501 CE.
- Drying program: fixed-time or automatic end point, fixed-weight or dry-mass drying mode, 95 mm sample pan, RS232 output; 290 × 180 × 140 mm.
Pharmacopoeia and compliance
Loss on drying measures all volatile matter and is a fast method for incoming-material and in-process checks; Karl Fischer titration measures water specifically. HQ-501 CE carries CE certification.
Frequently asked questions
How does a halogen moisture analyzer work?
It heats the sample with a halogen lamp and weighs it continuously; the weight lost on drying gives the moisture content.
What are the key specifications?
Range 0–100% moisture, accuracy ±0.5%, heating 60–160 °C (±2 °C), heating time 0–120 min, 95 mm sample pan, RS232 output.
Is a CE-certified version available?
Yes. HQ-501 CE offers the same halogen moisture analysis with CE certification.
Halogen moisture analyzer or Karl Fischer titrator?
Loss on drying measures all volatiles and is fast for powders and granules. Karl Fischer titration measures water specifically and reaches trace levels; see the KFT-50VC Karl Fischer titrator.
Related guides: Karl Fischer titrators · Granule moisture analysis with the HQ Series · Moisture control and tablet defects