Karl Fischer Titrator

Karl Fischer Titrator

Loss-on-drying and halogen moisture analyzers measure total volatile content, not water specifically — for compounds where that distinction matters, Karl Fischer titration is the reference method. Our KFT-50VC Karl Fischer Titrator supports both testing modes.

Key Features

  • Dual titration modes: Volumetric and Coulometric Karl Fischer, in a single benchtop unit
  • Moisture range from 3.0 μg to 250.0 mg depending on mode
  • Integrated oven sampling method for extended testing range

Applications

  • Trace water determination in coulometric mode (from 3.0 μg)
  • Applications where loss-on-drying methods are not suitable (e.g. volatile, heat-sensitive, or non-water-volatile compounds)

Explore the full lineup below to find the right solution for your lab. For quotation or technical support, contact our team.

How to choose a Karl Fischer titrator: volumetric or coulometric

Karl Fischer (KF) titration determines water content by a chemical reaction, so it measures water specifically rather than all volatiles. The KFT-50VC runs both volumetric and coulometric KF titration in one benchtop unit: volumetric mode covers 100 μg to 250.0 mg of water, coulometric mode 3.0 μg to 200 mg, and the oven sampling method handles gas, solid or liquid samples. The main choice is which mode matches the water content of your samples.

Model comparison

Mode Water range Resolution Typical use
Volumetric KF 100 μg – 250.0 mg 1 μg Samples with higher water content; titer determination built in
Coulometric KF 3.0 μg – 200 mg 0.1 μg Trace water
Oven sampling With either mode As per mode Constant or trace moisture in gas, solid or liquid samples

How to choose

  • Higher water content: volumetric mode (100 μg – 250.0 mg, 1 μg resolution), with automatic titration and KF titer determination methods.
  • Trace water: coulometric mode (from 3.0 μg, 0.1 μg resolution), with drift correction and a coefficient correction method.
  • Samples measured via an oven: oven titration and oven blank methods are available in both modes.
  • Fast routine checks of powders where total volatiles are acceptable: a halogen moisture analyzer (HQ Series) may be enough.
  • Data handling: 3-level user authority and password management, storage of up to 2,000 results, U-disk export as CSV or PDF, RS-232 printing and USB connection to a PC.

Pharmacopoeia and compliance

KFT-50VC is CE certified. Repeatability is ≤0.3% in both modes. Karl Fischer titration is a water-specific chemical method, unlike loss on drying, which measures all volatile matter. Results can be shown in μg, mg, %, ppm, mg/L or μg/mL.

Frequently asked questions

What is the difference between volumetric and coulometric Karl Fischer titration?
Volumetric titration adds iodine-containing titrant from a burette and suits higher water contents; coulometric titration generates iodine electrochemically and suits trace water. On the KFT-50VC: volumetric 100 μg – 250.0 mg, coulometric 3.0 μg – 200 mg.

Can one instrument do both?
Yes. The KFT-50VC includes a solvent manager, a 10 ml burette, a volumetric vessel, a coulometric vessel, measuring electrodes and a generator electrode.

Karl Fischer or loss on drying?
Loss on drying measures everything that evaporates when the sample is heated. Karl Fischer titration measures water only, which matters when samples contain other volatiles or when water is present at trace levels.

How are results stored and exported?
Up to 2,000 titration results are stored. Data can be exported to a U-disk as CSV or PDF, printed through RS-232, or transferred to a PC by USB.

Is the KFT-50VC CE certified?
Yes, the KFT-50VC is CE certified.

Related guides: Halogen moisture analyzers · Moisture control and tablet defects

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