Comparing Traditional vs Integrated ODF Manufacturing Models
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Comparing Traditional vs Integrated ODF Manufacturing Models
What makes an ODF production line truly pharma-ready?
1. Common Pitfalls in Traditional ODF Manufacturing
- Vague formulation responsibility between R&D and equipment supplier
- Layer separation or cracking due to poor drying curve design
- Difficulty scaling up from lab to production due to unmatched parameters
- No support for complex formulations (e.g., probiotics, multi-API)
2. HUANGHAI's Integrated Model: From Liquid to Packaged Film
- Joint Development: Co-develop stable ODF formulations with our engineers
- Process Matching: Parameter matching between pilot and industrial machines
- Real-World Drying: Heat gradient design using continuous hot-air tunnel (no need for multi-zone control)
- End-to-End Validation: From liquid preparation to final pouch-sealed product
3. Real Use Case
One client needed a heat-sensitive dual-API ODF. They failed in traditional systems due to delamination. Our natural hot-air drying tunnel, coupled with pilot testing and reformulation, helped them achieve >95% yield at scale.
4. Side-by-Side Comparison
| Dimension | Traditional Model | Integrated Model |
|---|---|---|
| Formulation Support | None | Joint development |
| Drying Design | Fixed zones | Heat gradient (no need for zone control) |
| Scale-up Risk | High | Low (matched pilot line) |
| Formulation Type | Simple mono-API | Multi-API, dual-action, probiotics |
| Support Scope | Equipment only | Equipment + formulation + scale-up |
Explore Full ODF Line Solutions
HUANGHAI offers end-to-end ODF systems from pilot-scale to commercial production. Explore below: