EZ320 ODF Film Cutting and Packaging Machine

Key Features

1. Uniquely designed bag-making mechanism allows printing on both sides of each pouch with precise alignment.
2. Direct membrane-to-pouch system ensures reliable transfer after slicing without intermediate transport issues.
3. Advanced continuous flat pressing heat-sealing mechanism with adjustable dwell time ensures excellent seal quality and broader material compatibility.
4. Open and visible mechanical design makes maintenance and troubleshooting easier.
5. Equipped with PLC controller and proprietary software system. Servo-driven operations for feeding, film pulling, sealing, and cutting ensure precision and stability.
6. Integrated longitudinal film cutting system for inline slicing.

Workflow

Film roll loading → Longitudinal slitting → Transverse cutting → Direct pouch insertion → Easy-tear pouch forming → Sealing → Final pouch cutting → Product output

Technical Specifications

Configuration & Components

A. Electrical Components

1. Color touchscreen (Xinje TG765G-UT)
2. Programmable logic controller (Xinje XD5-48T6)
3. 5 Servo motors (Xinje MS6S-80CS30B1-20P7)
4. 5 Servo drivers (Xinje DS5L-20P7-PTA)
5. Color mark positioning system (GDJ612(N)W/R, Shanghai Yatai)
6. Discharge motor (41K25RGN-C, Oubang)
7. Other electrical parts: relays, switches, buttons from Chint Electric

B. Mechanical Frame & Transmission Structure

1. Frame made of 40 × 40 × 2 mm 304 stainless steel square tubing.
2. Protective cover made from 1.2 mm thick 304 stainless steel sheet.
3. ODF film traction roller made of 316L stainless steel.

Frequently Asked Questions

Q: What is the difference between an ODF film and a transdermal patch?

A: Oral Dissolving Films (ODF) are placed on or under the tongue and dissolve within seconds to minutes, delivering APIs directly through the oral mucosa or via swallowing. Transdermal patches adhere to the skin and deliver APIs through the dermal layers into systemic circulation over hours to days. Despite different delivery routes, both are manufactured using similar solvent-cast film coating processes. Huanghai's MJ150 ODF machine supports both applications on a single platform with approximately 2 working days of changeover time.

Q: What production output can I expect from a Huanghai ODF machine?

A: The MJ150 produces 20,000 films/hour at commercial scale. The MJ150-L targets R&D and pilot production at 8,000–10,000 films/hour. For fully integrated lines, pair either machine with the MJF180 automatic cutting and packaging system (11,900 films/hr) or the more affordable EZ320 (9,000 films/hr). A complete MJ150 + MJF180 line can produce over 150 million finished pouches annually on a single-shift basis. Contact us for pricing and configuration details.

Q: What drying technology does Huanghai use for ODF production?

A: Huanghai uses patented gradient hot-air drying (Patent CN201668734U), which applies a smooth progressive temperature drop rather than stepwise oven zones used by competitors. This results in more uniform film thickness, reduced edge curl, and better API distribution across the film web. An optional far-infrared heating module adds 20–30% drying efficiency for solvent-based formulations. This patented drying system is one of the key technical advantages that justifies Huanghai's position as the preferred ODF equipment supplier to Sinopharm, Shanghai Pharma, and Fosun Pharma.

Q: What are the GMP requirements for ODF production equipment?

A: ODF manufacturing equipment must comply with cGMP (21 CFR Parts 210/211) for US market products, and equivalent standards (EU GMP Annex 1, ChGMP) for other markets. Key requirements: material contact surfaces must be 316L stainless steel or equivalent; CIP/SIP capability or documented cleaning validation; data integrity controls meeting ALCOA+ principles (audit trails, access control). Huanghai ODF machines meet these standards—all product contact surfaces use pharmaceutical-grade materials, and the control system includes operator access logs and parameter change records. Request our GMP compliance documentation.

Q: Can Huanghai machines produce stripe-coated or multi-formula ODF films?

A: Yes. Huanghai holds a patent for multi-formula stripe coating (Patent CN117323228A), enabling two different API formulations to be applied side-by-side in a single coating pass. This eliminates the need for multiple coating/drying cycles when producing combination-drug ODF products. Competitors require manual multi-layer coating with drying intervals between each formula. This capability is particularly valuable for fixed-dose combination products (e.g., dual-API ODFs for cardiovascular or CNS indications) where coating efficiency directly impacts production economics.