Patent Portfolio
Patent Portfolio
Built on 30+ Years of Pharmaceutical Engineering Innovation
About Academician Hou Huimin (侯惠民院士)
Huanghai Pharmaceutical Instruments was founded by and operates under the scientific leadership of Academician Hou Huimin (侯惠民院士), elected to the Chinese Academy of Engineering (CAE) in 1996 in the Medicine and Health Division — China's highest engineering honor in the pharmaceutical sciences.
Over a 30+ year career in pharmaceutical engineering research, Academician Hou Huimin has authored and co-authored 100+ patents spanning laser drilling for osmotic-pump tablets, ODF (oral dissolving film) coating systems, hot-air gradient drying, and multi-formula film formulations. His foundational work laid the basis for the equipment technologies that Huanghai Pharmaceutical Instruments commercializes today.
The patents listed below represent a curated selection of the most relevant granted and pending inventions — covering both patents held directly by Huanghai entities, and foundational patents invented by Academician Hou Huimin that underpin our equipment design philosophy.
Huanghai-Held Patents
The following patents are assigned to Huanghai corporate entities and reflect our direct investment in next-generation pharmaceutical manufacturing technology.
CN117323228A — Multi-Formula Stripe-Coating Technology for ODF
| Status | Patent Pending (filed 2023, under substantive examination since 2024-01-19) |
|---|---|
| Assignee | Shanghai Yellow Sea Testing Instrument Sales Co., Ltd. / Huanghai |
| Inventors | Academician Hou Huimin (侯惠民院士) and team |
| Technology | Enables simultaneous application of up to two distinct ODF formulations in a single coating pass, eliminating intermediate drying steps required by conventional multilayer processes. Incorporates a blade-coating mechanism (0.3–0.4 mm gap) with a four-zone hot-air drying system (30–150°C). |
| Application | MJ150 / MJ150-Lab ODF coating lines |
| Verify | patents.google.com/patent/CN117323228A/en |
CN119869871A — TDDS Coating-Drying-Lamination-Winding Integrated Equipment
| Status | Patent Pending |
|---|---|
| Assignee | Huanghai Zhizao (Shanghai) Technology Co., Ltd. |
| Technology | Integrated continuous-process equipment combining transdermal drug delivery system (TDDS) coating, drying, lamination, and winding operations in a single production unit, reducing material handling and contamination risk. |
| Application | Transdermal patch manufacturing lines |
| Verify | patents.google.com/patent/CN119869871A/en |
Foundational Patents by Academician Hou Huimin
The following patents were invented by Academician Hou Huimin (侯惠民院士) and assigned to affiliated pharmaceutical research institutes. They represent the core technical foundations from which our equipment designs derive. They are listed here because they are inseparable from understanding the engineering heritage of our products.
Academician Hou Huimin's Patent CN2642449Y — Pharmaceutical Laser Drilling for Osmotic-Pump Tablets (2003)
| Status | Expired (Lifetime) — technology in public domain; cited by 5 subsequent laser drilling patents industry-wide |
|---|---|
| Inventor | Academician Hou Huimin (侯惠民院士) and team |
| Technology | Computer-controlled automated laser drilling system for osmotic-pump controlled-release tablets, integrating photoelectric orientation detection, rotating carousel, camera-based quality inspection, and automatic sorting of conforming vs. defective tablets. This is the seminal patent for pharmaceutical laser drilling in China. |
| Application | Olando K3-2 laser drilling system design heritage |
| Verify | Academician Hou Huimin's foundational laser drilling patent: patents.google.com/patent/CN2642449Y/en |
CN201668734U — Hot-Air Gradient Drying for ODF (2010)
| Status | Expired (Lifetime, 2020) — technology in public domain |
|---|---|
| Inventor | Academician Hou Huimin (侯惠民院士) and team |
| Technology | Hot-air flow-based drying system for ODF coating machines achieving continuous operation and uniform film thickness. Covers the main chamber, auxiliary chamber, peristaltic pump, flat blade, conveyor belt, heating plate, exhaust fan, and winding mechanism configuration that remains the engineering basis of modern ODF dryers. |
| Application | MJ150 / MJ150-Lab / MJF180 ODF coating lines |
| Verify | patents.google.com/patent/CN201668734U/en |
Academician Hou Huimin's Patent CN2586476Y — Bilayer Adhesive Patch Coating (2002)
| Status | Expired (Lifetime, 2012) — earliest patent in the portfolio, reflecting 20+ years of continuous innovation |
|---|---|
| Inventor | Academician Hou Huimin (侯惠民院士) and team |
| Technology | Bilayer adhesive coating process for transdermal patch manufacturing, establishing the foundational approach to controlled-release adhesive film coating used in modern TDDS equipment. |
| Verify | Academician Hou Huimin's patent CN2586476Y: patents.google.com/patent/CN2586476Y/en |
CN117921216A — Auto-Flip Dual-Sided Laser Drilling System (2024)
| Status | Patent Pending (filed 2024) |
|---|---|
| Inventor | Academician Hou Huimin (侯惠民院士) and team |
| Technology | Automated tablet orientation recognition with pneumatic flip mechanism for dual-chamber osmotic-pump tablets, followed by laser drilling and multi-station inspection. Addresses the precision positioning challenge in high-efficiency double-sided laser drilling for osmotic-pump tablet manufacturing. |
| Application | Next-generation Olando K3-2 platform |
| Verify | patents.google.com/patent/CN117921216A/en |
CN103083284B — Effervescent Multi-Strip Film Formulation (Active to 2033)
| Status | Active (expires 2033-02-06) |
|---|---|
| Inventor | Academician Hou Huimin (侯惠民院士) and team |
| Technology | Alternating acid/alkaline stripe film combination dosage form that generates effervescence upon contact with water, masking bitter taste while improving drug dissolution rate. Particularly suitable for pediatric formulations and incompatible multi-component fixed-dose combinations — a direct complement to the multi-formula stripe-coating equipment capability. |
| Application | ODF R&D and fixed-dose combination (FDC) manufacturing |
| Verify | patents.google.com/patent/CN103083284B/en |
How These Technologies Translate to Our Equipment
The patents above are not abstract — each maps directly to an active product line.
| Equipment | Technology Foundation |
|---|---|
| Olando K3-2 (Laser Drilling) | Academician Hou Huimin's patent CN2642449Y (foundational laser drilling architecture, 2003) + Academician Hou Huimin's patent CN117921216A (auto-flip laser drilling, pending) |
| MJ150 / MJF180 / MJ150-Lab (ODF Coating) | CN201668734U (hot-air drying) + CN117323228A (multi-formula stripe coating, Huanghai-held, pending) |
| SY-6DN / RYJ / RCZ / CJY / LB / YPD (Pharmaceutical Testing) | 30+ years of pharmaceutical instrument engineering expertise, continuous refinement under Academician Hou Huimin's research program |
Independent Verification
All patents listed on this page can be independently verified via Google Patents. Each patent card above includes a direct link to the corresponding patent record. We encourage engineers, procurement teams, and regulatory affairs professionals to review patent details directly at:
Patent status (active, expired, pending) reflects the record as of the date of last registry audit. Pending patents are published applications under substantive examination; they confer patent-pending status but not yet granted rights.
Technical Inquiries
For technical details on how these patented technologies are incorporated into specific equipment models, or to discuss how our manufacturing solutions can meet your pharmaceutical production requirements, please contact us directly.