CJY-300E Tablet Friability Tester – Accurate Pharmaceutical Durability Testing Instrument

Tablet Friability Instruments

CJY-300E Tablet Friability Tester

The CJY-300E Tablet Friability Tester is an advanced pharmaceutical testing instrument used to assess the friability of tablets. Friability testing is vital to determine a tablet's resistance to abrasion and breakage during handling and transportation. The CJY-300E provides precise measurements, aiding pharmaceutical quality control laboratories in ensuring tablet durability and compliance with industry standards.

Description

The CJY-300E Tablet Friability Tester complies with the standards of the Chinese Pharmacopoeia and is designed for use in pharmaceutical manufacturing, research institutes, and hospitals. It evaluates the stability, abrasion resistance, and physical strength of tablets, making it an indispensable instrument for pharmaceutical quality testing.

 

Product Features

 

1. User-Friendly Design

   •  Equipped with a touch-screen human-machine interface for easy and intuitive operation.

   •  Bilingual (Chinese and English) interface to meet diverse user needs.

 

2. Precision and Reliability

   •  Adjustable rotation speed and customizable rotation range for flexible testing.

   •  Supports both clockwise and counterclockwise rotation for comprehensive evaluation.

 

3. Efficient and Safe Operation

   •  Operates quietly with low power consumption for enhanced safety and efficiency.

   •  Utilizes DC12V power supply with universal voltage adapter, ensuring reliability and compatibility.

 

4. Compliance and Certification

   •  Includes IQ/OQ certification documentation for validation.

 

Product Specifications

 

Parameter     Specification

l   Model    CJY-300E

l   Product Number 10102102

l   Number of Drums        2 drums

l   Drum Dimensions        Inner Diameter: 286mm, Depth: 39mm

l   Default Rotation Speed     25 RPM

l   Rotation Speed Range      20–50 RPM

l   Default Rotation Count      100 cycles

l   Rotation Count Range       1–1000 cycles

l   Rotation Direction        Clockwise/Counterclockwise

l   Power Supply       DC12V, 3.0A

 

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📄 Download User Manual

You can download the full user manual of the CJY-300E High-Speed Tablet Counting Machine below:

📥 Click here to download CJY-300E User Manual (PDF)

Note: Our lab instruments support basic audit trails strictly per USP/ChP standards.

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Frequently Asked Questions

Q: What does USP specify for tablet friability testing?

A: USP <1216> specifies that uncoated tablets are tested at 25 rpm for 100 rotations (4 minutes). The mass loss must not exceed 1.0% for most tablet types. Coated tablets follow modified procedures depending on coating type. The CJY-300E Friability Tester operates at adjustable speeds to meet both standard USP and modified test protocols. Important: the CJY-300E uses visual observation—results are recorded manually. For labs requiring electronic data capture for audit trails, integrate with a connected balance and LIMS system.

Q: What is an acceptable friability result for tablet release?

A: Per USP <1216>, a single test result of ≤1.0% mass loss is acceptable for most uncoated tablets. If one unit breaks or crumbles, re-test with the maximum value applying. For coated tablets, the specification is typically stricter: ≤0.5% is common for film-coated products, though the exact limit is formulation-specific. Friability failures often indicate problems with compression force, binder concentration, or moisture content—not just the test instrument.

Q: How does friability relate to tablet coating quality?

A: Friability measures mechanical robustness—tablets with high friability (>1%) will generate excessive dust and surface damage during coating pan tumbling, leading to uneven coat distribution and appearance defects. Pre-coating friability testing is therefore a critical in-process check. If core tablet friability exceeds 0.3–0.5%, reconsider the compression parameters (increase compaction force or binder level) before coating. This is especially important for enteric and modified-release coatings where surface imperfections compromise functional performance.

Q: Can the friability tester be used for effervescent tablets?

A: Yes, but with modified parameters. USP provides guidance for effervescent tablets: test 10 tablets at 100 rotations with a dehumidified drum to prevent premature reaction. The acceptable loss limit for effervescent formulations is typically ≤1.0% per USP <1216> Supplement. The CJY-300E supports variable speed (adjustable RPM) to accommodate these modified conditions. Contact us to discuss drum configurations for specialized tablet forms.