What Is Tablet Hardness Testing and Why Is It Critical for Pharma QC?
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Tablet hardness testing plays a crucial role in ensuring pharmaceutical tablets are strong enough to withstand handling while still disintegrating as intended for optimal drug absorption. This article explains why it matters and how to do it right.
Understanding Tablet Hardness Testing
Tablet hardness testing evaluates the mechanical integrity of tablets. It measures the force required to break a tablet under pressure, which reflects the tablet’s ability to endure manufacturing, packaging, and transportation stress without breaking or chipping.
Why It Matters for Quality Control
- Structural Integrity: Prevents breakage during handling and shipping.
- Dissolution Consistency: Ensures proper disintegration and absorption in the body.
- Regulatory Compliance: Meets pharmacopoeial requirements (e.g., USP, Ph. Eur., ChP).
Standard Testing Procedures
Tablet hardness is typically tested using dedicated instruments that apply force until the tablet fractures. These tests follow standardized methods defined by global pharmacopoeias.
Choosing the Right Hardness Tester
When selecting a hardness tester, consider:
- Accuracy and repeatability of readings
- Ease of calibration and operation
- Integration with weight and thickness testing
Related Instruments and Resources
For a full range of tablet testing instruments and automated solutions, visit our Pharmaceutical Testing Instruments Collection.