SY-6DN Intelligent 4-in-1 Tablet Tester – Hardness, Friability, Disintegration & Dissolution

Tablet Multi-Purpose Tester

SY-6DN Intelligent Tablet Multi-Purpose Tester

The SY-6DN is a powerful pharmaceutical testing instrument designed to perform comprehensive testing of tablets, including hardness, friability, disintegration time, and dissolution.

This multi-purpose tablet tester is ideal for use in pharmaceutical quality control labs, combining multiple test functions into one compact and intelligent device.

With full compliance to USP standards and intuitive automation, the SY-6DN improves efficiency and data accuracy in tablet analysis workflows.

As part of our complete line of pharmaceutical testing instruments, this all-in-one tester is a perfect solution for R&D, formulation testing, and batch inspection in drug production environments.

Description

The SY series intelligent tablet multi-purpose tester has been applied in the field of pharmaceutical analysis for over 40 years. It strictly complies with the current standards of the Chinese Pharmacopoeia. The SY-6DN model integrates four test functionalities: dissolution testing, disintegration testing, hardness testing, and friability testing. It is widely used in pharmaceutical enterprises, scientific research institutions, and higher education organizations.

 

Product Features

   •  Multi-functionality: Combines dissolution testing, disintegration testing, hardness testing, and friability testing into one system.

   •  Enhanced Efficiency: Ideal for pharmaceutical enterprises, ensuring optimal efficiency in quality assurance processes.

   •  Data Security and Traceability: Built-in user-level access control, audit trails, and test record management, with the ability to export reports via USB.

   •  User-Friendly Interface: Features a touch-screen control panel with bilingual (Chinese and English) operation for ease of use.

   •  Precision Control: Real-time temperature monitoring, independent testing for each dissolution vessel, and precise calibration capabilities.

   •  Robust Design: Includes modular design for quick replacement of consumables, advanced pipe routing for operational safety, and specialized medical-grade connectors for dissolving heads.

   •  Customizable Options: Supports additional configurations for further customization based on user needs.

   •  Compliance Certification: Supplied with IQ/OQ certification documentation for regulatory compliance.

 

Technical Specifications

 

Dissolution Testing Parameters Specifications

Number of Channels 6

Shaft Vertical Runout <0.5mm

Shaft Rotation Deviation   <1.0mm

Shaft and Cup Concentricity   <1.0mm

Rotation Speed Range      10–300 RPM

Stability  ≤±1%

Sample Volume  <100mL

Sampling Interval ≤9999 seconds

 

Disintegration Testing Parameters Specifications

Number of Baskets     1/6

Testing Frequency      30–32 cycles/min

Basket Stroke Distance      55±1.0mm

Minimum Distance Between Base and Net        25±1.0mm

Net Aperture Diameter      2.0mm

Temperature Range   Room Temperature to 45°C

Timer Accuracy   ≤0.3°C

 

Hardness Testing Parameters Specifications

Testing Range      10–350N

Resolution     0.01N

Accuracy     ±1.5%±1 digit

Diameter Testing Range    2–25mm

 

Friability Testing Parameters Specifications

Number of Rotating Wheels     1

Wheel Diameter  286mm

Default Rotation Speed     25 RPM

Speed Range      20–50 RPM

Power Supply       AC220V±10%, 50Hz

Note: Our lab instruments support basic audit trails strictly per USP/ChP standards.

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Frequently Asked Questions

Q: What is the USP standard for disintegration testing?

A: Disintegration testing is governed by USP <701> (tablets and capsules) and ChP 0921. The test measures the time for a dosage form to break into particles small enough to pass through a specified mesh screen under simulated GI conditions. USP <701> requires testing in water or simulated gastric fluid at 37°C ± 2°C, with a reciprocating basket assembly. Huanghai LB-series testers are engineered to meet these parameters, with temperature-controlled water baths maintaining ±0.5°C accuracy.

Q: What is the difference between the LB-2D and LB-3D disintegration testers?

A: The LB-2D is a 2-station tester with a touchscreen interface—suited for small labs or single-product testing. The LB-3D adds a third station, enabling three simultaneous product tests, and includes an audit trail and data management system for GMP compliance. Choose LB-2D for budget-constrained or low-throughput environments; upgrade to LB-3D when your lab handles multiple formulations simultaneously or requires traceable electronic records for regulatory submissions. Contact us for pricing.

Q: How does disintegration testing differ from dissolution testing?

A: Disintegration measures whether a dosage form physically breaks apart within a specified time—it does not measure how much API is released. Dissolution (USP <711>) measures the rate and extent of API release into solution, which directly correlates with bioavailability. Disintegration is faster (typically 5–30 minutes) and is used as a routine in-process check; dissolution is the definitive QC test for bioavailability prediction. Many tablets that disintegrate quickly still have poor dissolution if the API is poorly soluble—disintegration alone is not sufficient for bioavailability assessment.

Q: Can the disintegration tester be used for suppositories or capsules?

A: Yes. The LB-series testers support both tablet and capsule disintegration per USP <701>. For suppositories, the method differs—disintegration is measured using the melting time method (ChP 融变时限), which requires a different instrument: the RBY-N Melting Time Tester. The RBY-N provides three parallel test units with adjustable rotation frequency, suitable for lipid-based suppository matrices. For complete lab capability, pair the LB-3D with the RBY-N to cover solid oral and rectal dosage forms.