LB-3D Intelligent Disintegration Tester – High-Performance Pharmaceutical Testing Equipment

Disintegration Instruments

LB-3D Intelligent Disintegration Tester

The LB-3D Intelligent Disintegration Tester is a state-of-the-art pharmaceutical testing instrument designed for accurate assessment of tablet and capsule disintegration times. Compliant with USP and other pharmacopoeia standards, this disintegration tester features advanced automation and user-friendly controls, making it ideal for pharmaceutical quality control laboratories. As part of our comprehensive range of pharmaceutical testing instruments, the LB-3D ensures consistent and reproducible results, enhancing the efficiency of your pharmaceutical analysis processes.

Description

The LB series intelligent disintegration tester has been applied in the field of pharmaceutical analysis for over 40 years. Fully compliant with the latest Chinese Pharmacopoeia standards, it is specifically designed to test the disintegration properties of solid dosage forms such as tablets, sugar-coated tablets, film-coated tablets, enteric-coated tablets, pills, and capsules under specified conditions.

 

Product Features

 

1. Advanced Data Management

   •  Built-in three-tier user permissions, audit trails, and test record management.

   •  USB connectivity supports direct test data export for reporting.

   •  Frequently used data can be stored for quick and efficient use.

 

2. High-Precision Temperature Control

   •  Real-time temperature monitoring with dual-layer temperature protection and calibration functionality.

   •  Preheating functionality allows users to schedule start times for heating.

 

3. Optimized System Design

   •  Professional-grade circulation pipeline for efficient operation.

   •  Fully compliant with pharmacopoeia standards.

 

4. Compliance and Certification

   •  Includes IQ/OQ certification documentation for validation.

 

Product Specifications

 

l   Parameter    Specification

l   Model    LB-3D

l   Product Number 10107104

l   Disintegration Stations       3 stations (6 tubes)

l   Basket Reciprocation Speed   25–35 strokes/min

l   Basket Reciprocation Range   55±1.0mm

l   Minimum Basket Distance 25±1.0mm

l   Sieve Aperture    Standard: 0.42mm, Optional: 0.71mm, 1.0mm

l   Adjustment Range     Room temperature to 45.0°C

l   Temperature Uniformity     0.1°C

l   Control Precision ±0.3°C

l   Cycle Limit   <100 cycles

l   Cycle Time   ≤999.9h/59min59s

l   Power Supply       AC220V±10%, 50Hz

 

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📄 Download User Manual

You can download the full user manual of the CJY-300E High-Speed Tablet Counting Machine below:

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📄 Download User Manual

You can download the full user manual of the LB-3D Intelligent Disintegration Tester below:

📥 Click here to download LB-3D User Manual (PDF)

Note: Our lab instruments support basic audit trails strictly per USP/ChP standards.

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Frequently Asked Questions

Q: What is the USP standard for disintegration testing?

A: Disintegration testing is governed by USP <701> (tablets and capsules) and ChP 0921. The test measures the time for a dosage form to break into particles small enough to pass through a specified mesh screen under simulated GI conditions. USP <701> requires testing in water or simulated gastric fluid at 37°C ± 2°C, with a reciprocating basket assembly. Huanghai LB-series testers are engineered to meet these parameters, with temperature-controlled water baths maintaining ±0.5°C accuracy.

Q: What is the difference between the LB-2D and LB-3D disintegration testers?

A: The LB-2D is a 2-station tester with a touchscreen interface—suited for small labs or single-product testing. The LB-3D adds a third station, enabling three simultaneous product tests, and includes an audit trail and data management system for GMP compliance. Choose LB-2D for budget-constrained or low-throughput environments; upgrade to LB-3D when your lab handles multiple formulations simultaneously or requires traceable electronic records for regulatory submissions. Contact us for pricing.

Q: How does disintegration testing differ from dissolution testing?

A: Disintegration measures whether a dosage form physically breaks apart within a specified time—it does not measure how much API is released. Dissolution (USP <711>) measures the rate and extent of API release into solution, which directly correlates with bioavailability. Disintegration is faster (typically 5–30 minutes) and is used as a routine in-process check; dissolution is the definitive QC test for bioavailability prediction. Many tablets that disintegrate quickly still have poor dissolution if the API is poorly soluble—disintegration alone is not sufficient for bioavailability assessment.

Q: Can the disintegration tester be used for suppositories or capsules?

A: Yes. The LB-series testers support both tablet and capsule disintegration per USP <701>. For suppositories, the method differs—disintegration is measured using the melting time method (ChP 融变时限), which requires a different instrument: the RBY-N Melting Time Tester. The RBY-N provides three parallel test units with adjustable rotation frequency, suitable for lipid-based suppository matrices. For complete lab capability, pair the LB-3D with the RBY-N to cover solid oral and rectal dosage forms.