HY-4000 Freezing-Point Osmometer

HY-4000 Freezing-Point Osmometer — Precision Osmolality Testing

The HY-4000 Freezing-Point Osmometer is a precision instrument used to measure the osmotic concentration of a solution (osmolality). It was co-developed by Huanghai together with leading Chinese medical universities and research institutes, purpose-built to deliver high-precision, high-stability osmotic solution testing for pharmaceutical, biomedical, and academic/research applications.

Regulatory Compliance

Fully compliant with current Chinese Pharmacopoeia (ChP) standards. Meets the safety requirements of GB4793.1-2007 and the YY0648-2008 in-vitro diagnostic (IVD) medical device standard, supporting laboratory data integrity and operational safety.

Applications

• Pharmaceutical & biologics manufacturers: pharmacological analysis of traditional Chinese medicine, R&D/production/QC of drugs and reagents — aligned with the Pharmacopoeia's inclusion of osmolality testing as a regulatory test method
• Universities & research institutes: chemistry and biophysics teaching, and R&D/production across agricultural soil science, plant physiology, animal husbandry, aquaculture breeding selection, health products, and the beverage industry

Features

• Microcomputer control: automated microcomputer control system with a fully Chinese-language menu and clear step-by-step process guidance
• HD interactive display: 4.3" industrial-grade color touchscreen with real-time display of measurement status and key test data
• Data traceability output: built-in integrated printer (except on the basic/simplified variant) for quick data printing

Specifications

Measurement Range: 0-4000 mOsm/kg

Sample Volume: 0.5 mL

Measurement Speed: 3 min/test

Resolution: 0.1 mOsm/kg

Cooling Method: Semiconductor (thermoelectric) cooling — no external chiller water required

Probe Lift: Automatic (manual on the basic/simplified variant)

Basic Measurement Error: ±3 mOsm/kg (≤300 mOsm/kg); ±1.0% (>300 mOsm/kg)

Repeatability / Cross-Contamination: ≤1%

Weight / Dimensions: 15 kg / 480 × 350 × 300 mm

Power Supply: 220V, 50Hz / 135VA

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Frequently Asked Questions

Q: What is the measurement range and how much sample does the HY-4000 need?

A: The HY-4000 measures 0-4000 mOsm/kg with a resolution of 0.1 mOsm/kg, using a sample volume of just 0.5 mL per test. Each measurement takes about 3 minutes. Contact us to discuss your specific testing throughput needs.

Q: Is the HY-4000 compliant with Chinese Pharmacopoeia requirements?

A: Yes. The HY-4000 is fully compliant with current Chinese Pharmacopoeia (ChP) standards, and also meets the GB4793.1-2007 safety standard and the YY0648-2008 in-vitro diagnostic (IVD) medical device requirements. Contact us for documentation to support your regulatory environment.

Q: Does the HY-4000 need external cooling water?

A: No. The HY-4000 uses semiconductor (thermoelectric) cooling, so no external chiller water connection is required. The probe lifts automatically on the standard model (the basic/simplified variant uses a manual lift). Contact us to discuss which configuration fits your lab.