Olando K3-2 Laser Drilling System: Bi-Layer Precision & Vision Inspection

Introduction

Controlled-release formulations, especially osmotic pump tablets (OROS), demand pinpoint accuracy. A slight deviation in hole depth or position can alter the dissolution profile, rendering the batch useless. The Olando K3-2 Pharmaceutical Laser Drilling System delivers 0.9 mm blind/through-hole precision with ±0.1 mm accuracy.

What Is the Challenge with Bi-Layer Tablets?

Standard laser drills often struggle with bi-layer tablets. If the tablet tumbles incorrectly, a standard machine might drill into the "push layer" instead of the "drug layer," destroying the release mechanism.

The Solution: Olando K3-2 Technical Deep Dive

1. Patented Laser-Drilling Technology (Academician Hou Huimin's patent CN2642449Y)

The Olando K3-2 uses patented laser-drilling technology (Academician Hou Huimin's patent CN2642449Y).

2. Single/Double-Side Drilling, Accuracy and Speed

- Flexibility: Supports both single-sided and dual-sided drilling.
- Precision: Achieves an aperture accuracy of ±0.1 mm.
- Speed: Capable of processing up to 120,000 tablets/hour (based on a 15 mm tablet).

Why It Matters: Inline Inspection and Rejection

In high-value pharmaceutical production, rejecting bad tablets after packaging is too late. The K3-2 integrates dual-station vision inspection (closed-loop, real-time rejection).
- Real-Time Inspection: Dual-station vision inspection with tablet defect detection.
- Automatic Rejection: Integrated inspection and rejection system.
- Audit Ready: Full data logging — 21 CFR Part 11 ready (designed to support audit trail, electronic records, and access control requirements; final compliance is established through end-user validation).

Conclusion

Precision laser drilling is not just about making a hole; it's about defining the drug's therapeutic performance. With the Olando K3-2, you gain control over that performance.

Discover the Olando K3-2 System →

Frequently Asked Questions

Q: What aperture tolerance and throughput can the K3-2 achieve?

A: The system achieves an aperture accuracy of ±0.1 mm at up to 120,000 tablets per hour (based on a 15 mm tablet).

Q: Can the same machine switch between single-side and double-side drilling?

A: Yes — the Olando K3-2 supports both single-sided and dual-sided drilling.

Q: What happens to tablets with a defective laser-drilled hole?

A: Dual-station vision inspection with tablet defect detection and an integrated inspection and rejection system (closed-loop, real-time rejection), with data logging designed to support audit trail and electronic-record requirements.